Metabolism factors and binge eating, obesity, diet, weight

Fat Shaming Tied to Increased Risk of Metabolic Problems  Medscape (Feb 3, 2017) by Lisa Rapaport – Obese people who feel stigmatized about their size may be at increased risk for metabolic syndrome, a new study suggests. Weight stigma is a chronic stressor that may increase cardiometabolic risk. Some individuals with obesity self-stigmatize, but no study to date has examined whether this might be associated with metabolic syndrome, the authors note in their January 26 online paper in Obesity. … more

New theory on how insulin resistance, metabolic disease begin  ScienceDaily (Sept 26, 2016) – Does eating too much sugar cause type 2 diabetes? The answer may not be simple, but a study adds to growing research linking excessive sugar consumption — specifically the sugar fructose — to a rise in metabolic disease worldwide. The study, conducted in mice and corroborated in human liver samples, unveils a metabolic process that could upend previous ideas about how the body becomes resistant to insulin and eventually develops diabetes. … more

Is ‘when we eat’ as important as ‘what we eat’?  ScienceDaily  (June 22, 2016) – In a review of research on the effect of meal patterns on health, the few studies available suggest that eating irregularly is linked to a higher risk of metabolic syndrome (high blood pressure, type 2 diabetes and obesity). The limited evidence highlights the need for larger scale studies to better understand the impact of chrono-nutrition on public health, argue the authors of two new papers …. more

‘Healthy’ foods differ by individual   ScienceDaily (Nov 19, 2015) – Ever wonder why that diet didn’t work? A new study tracking the blood sugar levels of 800 people over a week suggests that even if we all ate the same meal, how it’s metabolized would differ from one person to another. The findings demonstrate the power of personalized nutrition in helping people identify which foods can help or hinder their health goals. … more

Obesity breakthrough: Metabolic master switch prompts fat cells to store or burn fat  ScienceDaily (Aug 19, 2015) – Obesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone, and contributes to potentially fatal disorders such as cardiovascular disease, type 2 diabetes, and cancer. Scientists have now revealed the mechanism underlying the genomic region most strongly associated with obesity. The findings uncover a genetic circuit that controls whether our bodies burn or store fat. Manipulating that genetic circuit may offer a new approach for obesity treatments. …more

Certain gut bacteria may induce metabolic changes following exposure to artificial sweeteners   ScienceDaily (Sept 17 , 2014) — Artificial sweeteners have long been promoted as diet and health aids. But breaking research shows that these products may be leading to the very diseases they were said to help prevent: scientists have discovered that, after exposure to artificial sweeteners, our gut bacteria may be triggering harmful metabolic changes. more …

A carefully scheduled high-fat diet resets metabolism and prevents obesity, researchers find   ScienceDaily (Sep. 12, 2012) — New research from the Hebrew University of Jerusalem shows that a carefully scheduled high-fat diet can lead to a reduction in body weight and a unique metabolism in which ingested fats are not stored, but rather used for energy at times when no food is available.   Link

Obesity and metabolic syndrome associated with impaired brain function in adolescents   ScienceDaily (Sep. 3, 2012) — A new study by researchers at NYU School of Medicine reveals for the first time that metabolic syndrome (MetS) is associated with cognitive and brain impairments in adolescents and calls for pediatricians to take this into account when considering the early treatment of childhood obesity.   Link

What babies eat after birth likely determines lifetime risk of metabolic mischief and obesity, rat studies suggest    ScienceDaily (Aug. 30, 2012) — Rats born to mothers fed high-fat diets but who get normal levels of fat in their diets right after birth avoid obesity and its related disorders as adults, according to new Johns Hopkins research. Meanwhile, rat babies exposed to a normal-fat diet in the womb but nursed by rat mothers on high-fat diets become obese by the time they are weaned.   Link

Obesity, metabolic factors linked to faster cognitive decline    ScienceDaily (Aug. 20, 2012) — People who are obese and also have high blood pressure and other risk factors called metabolic abnormalities may experience a faster decline in their cognitive skills over time than others, according to a study published in the August 21, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.   Link

Obesity not always tied to higher heart risk    Reuters Health (May 24, 2012)  by Aparna Narayanan – An obese person isn’t inevitably at increased risk of cardiovascular disease and death, a new U.K. study finds. “The people really at risk are the ones who have obesity in combination with other metabolic health risk factors” … The results are in line with most previous research that defined metabolic health as having normal levels of markers like blood pressure, blood sugar, HDL, or “good” cholesterol, and C-reactive protein, which is a measure of inflammation in the body.  “People with good metabolic health are not at risk of future heart disease — even if they are obese” …  Link

Extended daily fasting overrides harmful effects of a high-fat diet: Study may offer drug-free intervention to prevent obesity and diabetes  ScienceDaily (May 17, 2012) — It turns out that when we eat may be as important as what we eat …regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice. In a paper … in Cell Metabolism, scientists from Salk’s Regulatory Biology Laboratory reported that mice limited to eating during an 8-hour period are healthier than mice that eat freely throughout the day, regardless of the quality and content of their diet …The study sought to determine whether obesity and metabolic diseases result from a high-fat diet or from disruption of metabolic cycles.   Link

Faulty fat sensor implicated in obesity and liver disease  ScienceDaily (Feb. 19, 2012) — Defects in a protein that functions as a dietary fat sensor may be a cause of obesity and liver disease, according to a study published in the journal Nature, led by researchers at Imperial College London. The findings highlight a promising target for new drugs to treat obesity and metabolic disorders.  Link

Health benefits of exercise my depend on cellular degradation  ScienceDaily (Jan. 20, 2012) – The health benefits of exercise on blood sugar metabolism may come from the body’s ability to devour itself, UT Southwestern Medical Center researchers report in the journal Nature.  Link

Intestinal bacteria drive obesity and metabolic disease in immune-altered mice    ScienceDaily (Mar. 8, 2010) — Increased appetite and insulin resistance can be transferred from one mouse to another via intestinal bacteria, according to research being published online by Science magazine.  The finding strengthens the case that intestinal bacteria can contribute to human obesity and metabolic disease, since previous research has shown that intestinal bacterial populations differ between obese and lean humans.  Link

When you eat may be just as vital to your health as what you eat  ScienceDaily (Nov. 26, 2009) — When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands of genes in the liver — the body’s metabolic clearinghouse — is mostly controlled by food intake and not by the body’s circadian clock as conventional wisdom had it.  Link

‘Spoonful of sugar’ makes the worms’ life span go down   ScienceDaily (Nov. 5, 2009) — If worms are any indication, all the sugar in your diet could spell much more than obesity and type 2 Diabetes. Researchers reporting in the November issue of Cell Metabolism… say it might also be taking years off your life.  Link

Eating quickly is associated with overeating, study indicates   ScienceDaily (Nov. 4, 2009) — According to a new study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM), eating a meal quickly, as compared to slowly, curtails the release of hormones in the gut that induce feelings of being full. The decreased release of these hormones, can often lead to overeating.  Link

Fatty foods – not empty stomach – fire up hunger hormone   ScienceDaily (June 8, 2009) — New research led by the University of Cincinnati (UC) suggests that the hunger hormone ghrelin is activated by fats from the foods we eat—not those made in the body—in order to optimize nutrient metabolism and promote the storage of body fat.  The findings, the study’s author says, turn the current model about ghrelin on its head and point to a novel stomach enzyme (GOAT) responsible for the ghrelin activation process that could be targeted in future treatments for metabolic diseases.  Link

Avoiding the midlife diet crisis: Beat a slowing metabolism with some easy nutrition fixes (May 29, 2009) by Bonnie Taub-Dix, R.D. — While time may adorn you with new lines on your face, a new color hair (gray) and a new waistline, the passing decades are not to blame for all of the changes in your body. Your eating habits, your attitude and your approach to everyday experiences also play key roles.  Link

Exercise not likely to rev up your metabolism:  Studies bust myth that working out gives you a fat-burning boost (May 26, 2009) by Jacqueline Stenson  — Start exercising and you’ll become a round-the-clock, fat-burning machine, right? That’s long been a commonly held belief among exercisers and fitness experts alike. But a new report finds that, sadly, it’s not very likely.  The notion that exercise somehow boosts the body’s ability to burn fat for as long as 24 hours after a workout has led to a misperception among the general public that diet doesn’t matter so much as long as one exercises…   Link

Vitamins found to curb exercise benefits  New York Times (May 11, 2009) by Nicholas Wade — If you exercise to improve your metabolism and prevent diabetes, you may want to avoid antioxidants like vitamins C and E.  That is the message of a surprising new look at the body’s reaction to exercise, reported on Monday by researchers in Germany and Boston.  Link

Brain enzyme may play key role in controlling appetite and weight gain  ScienceDaily (Dec. 16, 2008) — Researchers at Albert Einstein College of Medicine of Yeshiva University have found that overactivity of a brain enzyme may play a role in preventing weight gain and obesity. The findings were reported in Cell Metabolism.  Link

Study: Six new gene mutations linked to obesity (Dec. 14, 2008) — Researchers have identified six new gene mutations linked to obesity and said on Sunday they point to ways the brain and nervous system control eating and metabolism.  Link